The 38-year-old was in a mood after opening the scoring nine minutes into the game for Robert Martinez’s side.
Joao Felix and Bernardo Silva were also on the scoresheet to make it 3-0 for the 2016 European champions before Ronaldo notched his second and Portugal’s fourth early in the second half.
It was the Al-Nassr superstar’s first goal that caught the attention of viewers and fans watching at Stade de Luxembourg.
The Real Madrid and Manchester United legend raced away towards the left corner as he often does before producing his trademark ‘siuuu’ celebration.
As the five-time Ballon d’Or winner landed from his spin, he mixed it up with his other celebration, crossing his hands across his chest, a slight variation on the interlocking fingers.