The 26-year-old felt some discomfort and limped off as he was replaced by Rodrigo Battaglia at half-time.
The injury comes at a crucial time as Iddrisu had been included in Ghana’s yet-to-be-announced final squad for the World Cup.
The Mallorca midfielder has been a mainstay in the Black Stars under Otto Addo featuring in both the Brazil and Nicaragua friendlies.
The extent of the injury is unknown but Otto Addo is obliged to name his squad by November 13.
Ghana face Switzerland in a friendly just seven days before they begin their World Cup journey against Portugal on November 24.
Ghana will also play South Korea and Uruguay.